Rabies and seizure disorders may cause ptyalism. Uremia associated with kidney disease also produces excessive salivation. When a cat or dog has liver failure or dysfunction, the owner will likely notice other associated behavioral changes as well. Ptyalism is a common sign of hepatic encephalopathy associated with portosystemic shunt, a vascular abnormality involving the liver. Cat and dog patients with liver or kidney dysfunction may salivate excessively because of metabolic toxins that are not cleared by these organs. Cats with feline leukemia will experience ptyalism as well. Neoplasms (tumors), foreign bodies, viral upper respiratory infections, and a number of immune-mediated conditions may also cause excessive salivation. Most affected cats will display some signs of oral pain or eating difficulty if there is significant dental or gum disease, but these signs are sometimes overlooked.
Gingivitis and stomatitis (inflammation of the gums and oral cavity, respectively) are common problems of cats. Ulcers and other erosions of the oral cavity, gum disease, stomach ulcers, and throat irritation from numerous causes are all likely to cause excessive salivation. Gastrointestinal irritation or inflammation frequently stimulates the salivary glands to oversecrete. Problems of several body systems may cause this.ĭiseases of the digestive tract (especially the oral cavity, throat or esophagus), the liver and the central nervous system may produce excessive salivation.
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